A-B Hemolytic Disease of the Newborn

Blueberry Muffin Rash in a Patient with Hemolytic Disease of the Newborn Due to Anti-Cw

Blueberry muffin rash is a characteristic multiple bluish skin nodules associated with perinatal infection, severe and chronic anemia, and neoplastic infiltrative diseases. We present an unusually severe case of hemolytic disease of the newborn. He required exchange transfusions for several times. The complete work up led to the diagnosis of anti-Cw. The skin lesion regressed spontaneously with...

Hemolytic Disease of the Newborn

Hemolytic disease of the newborn (HDN), with high potential for increased fetal loss is less common now, due to the universal screening for iso-sensitization and also because of appropriate use of antenatal anti-RhD antibody prophylaxis. There are other non-RhD antibodies that can cause HDN. In US, we occasionally encounter a highly sensitized fetus with significant morbidity and mortality. In ...

Immunologic Basis and Immunoprophy-laxis of RhD Induced Hemolytic Disease of the Newborn (HDN)

RhD antigen is the most immunogenic and clinically significant antigen of red blood cells after ABO system. It has historically been associated with hemolytic disease of the newborn (HDN) which is now routinely prevented by the administration of polyclonal anti-D immunoglobulin. This management of HDN has proven to be one of the most successful cases of prophylactic treatment based on antibody ...

[prevention of Hemolytic Disease of the Newborn].

Erythrophagocytosis in hemolytic disease of the newborn.

By MARY B. COOPER, B.A., M.T. (ASCP) I N 1909, Buchan and Comrie” reported the occurrence of erythrophagocytes in the peripheral blood of 2. newborn infants with ‘ ‘congenital anemia and enlargement of the spleen. ‘ ‘ In 193 I , Abt2 described these cells in blood smears of a case of anemia of the newborn. In 1938, Wyatt, Cooper and Groat9 reported 3 cases of the same disease in which the cells...